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Sales Contacts For advertising information contact: Alan El Faye
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| IN THIS ISSUE |
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Broad Institute Secures Future with $400 Million Endowment |
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SAS Takes Lifecycle View of Patient Safety Data |
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Outsourcing the Drug Industry |
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September Cover Story: There Is Only One IBM
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November Bio-IT World Issue Preview
PERSONAL GENOMICS – November marks the first anniversary of the launch of consumer genomics services. Kevin Davies examines the progress and challenges of this revolution in the delivery of predictive medical information.
THE NEXT GENERATION – Highlights from CHI’s four-day conference on next-generation sequencing and data analysis in Providence, RI.
SUPERCOMPUTING – A special supplement on trends in high-performance computing.
To advertise, contact Alan El Faye at 213-300-3886, Kay O. Christopher at 860-693-2991, or Tom Loughran at 781-972-5482. Ad Closing: Oct. 2, 2008
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| THIS WEEK IN BIO-IT |
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Broad Institute Secures Future with $400 Million Endowment By Kevin Davies
CAMBRIDGE – Billionaire philanthropist Eli Broad and his wife Edythe have announced a new $400 million endowment that secures the future of the Broad Institute.
The announcement was made on the institute’s fourth anniversary by Eli Broad in the packed lobby of the building. “This country has been more than good to us,” he said. “It’s a privilege and a responsibility to give back some of our financial resources to make the world a better place.”
Broad said his gift would ensure that the work would continue, making the institute “the place where the greatest discoveries take place.” He hoped that his total gifts of $600 million would rise to the $1 billion mark, enabling Broad researchers to continue making headway in the fight to improve human health. To which Broad Institute founding director Eric Lander could just say, “Wow!” Read more.
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SAS Takes Lifecycle View of Patient Safety Data By Ann Neuer
The pharmaceutical industry and regulatory agencies are sharpening their focus on patient safety through intense efforts to improve the way safety data are collected, analyzed and interpreted. And there is a long way to go, says Jason Burke, global director of the health and life sciences market segments at SAS. “Today, most organizations do separate analyses for drugs before and after approval. This is a challenge because it may not be obvious how the lifecycle of a drug looks when safety analyses are conducted using separate pre- and post-approval processes and systems,” Burke explains. Read more.
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Last Week's Most-Read Bio-IT World Story Playing it SAFE is a Leadership Move for AstraZeneca
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Bio-IT Briefs - Sept. 8, 2008
- NIH funds nine centers to speed identification of small-molecule probes
- Grand Challenges Explorations, Round 2, now accepting proposals
- HTG introduces multiplexed mini-microarray solution
- Rosetta Genomics identifies potential microRNA biomarkers in blood serum
- eGenomics awarded patent for rapid DNA sequencing platform to control hospital-acquired infections . . . more
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| ELSEWHERE IN THE PRESS |
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Outsourcing the Drug Industry
U.S. giants are rushing to partner with Indian and Chinese companies—tapping their brainpower and saving millions of dollars in the search for breakthrough treatments. Businessweek.
Studies Spot Numer Undiscovered Gene Alterations in Pancreatic and Brain Cancers
HHMI investigators have detected a multitude of broken, missing, and overactive genes in pancreatic and brain tumors, in the most detailed genetic survey yet of any human tumor. HHMI News.
Biogen and Elan Start Testing Tysabri in Cancer
Biogen Idec Inc. and Elan Corp. PLC said they have started the first clinical trial of their multiple sclerosis and Crohn's disease drug Tysabri as a treatment for cancer. Boston Globe.
Pfizer Acquires Rights to Alzheimer's Drug
Pfizer said Wednesday that it was acquiring the rights to a promising experimental drug for Alzheimer’s disease from Medivation for as much as $725 million. New York Times.
Big Pharma Gravitates to the Academe
Beset by drug failures and limited late-stage pipelines, big pharmaceutical companies are increasingly looking outside their own walls for scientific discoveries by partnering with academic institutions. Financial Times.
Gene Map of Europe May Deepen Understanding of Diseases
Scientists have shown that they can use genomic analysis to pinpoint a person's geographical origins to within just a few hundred kilometers. MIT’s Technology Review.
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BIO-IT WORLD SEPTEMBER 2008
ISSUE HIGHLIGHTS |
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COVER STORY There Is Only One IBM By John Russell
Trying to describe in a single story the full scope of IBM’s Life Sciences and Healthcare activities and related work being done by IBM Research is at best ambitious and at worst foolhardy. Big Blue may be unique in the corporate world in terms of the sheer number, diversity, and depth of its activities.
IBM revenues will top $100 billion this year, with services accounting for more than half ($54 billion in ’07). Although the Americas still make up the largest piece of the pie, Asia/Pacific, Europe, Middle East, and Africa collectively contribute almost 60% of revenues. Headcount is around 388,000, with rapidly growing encampments in India (94,000 by year’s end) and China (already IBM’s global procurement headquarters). By most measures—profits, cash, earnings per share, margins, etc.—IBM is in excellent health despite the macro economic malaise in Europe and North America and volatility within the IT sector. Read more.
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FIRST BASE
Enlight's Model Starts Making Sense By Kevin Davies
The headlines surrounding the pharmaceutical industry this summer have made for pretty grim reading. The specter of downsizing swirls around big pharmas such as Pfizer, GlaxoSmithKline, and many others. Drug safety issues have surfaced again with Biogen Idec’s multiple sclerosis drug Tysabri. And the dearth of solid candidates in the pipelines is a key reason why pharmas are offering lavish sums for biotechs such as Genentech and ImClone.
Against this backdrop, the unprecedented model surrounding the creation and mission of Enlight Biosciences stands out a mile. As we report in this issue, Enlight is a technology development company cofounded by Merck, Pfizer, and Eli Lilly. The three pharma partners—one or two others may yet join—have invested in a for-profit company that aims to develop enabling tools and technologies for pharma customers. The founders will enjoy early access to those technologies. Read more.
From Our Archives: The July/August issue of Bio-IT World.
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LIFE SCIENCE JOBS
Isilon Systems ~ Senior Marketing Communications Manager Isilon Systems is the worldwide leader in clustered storage systems and software for digital content and unstructured data. We seek an experienced marketing communications professional/writer expert in creating and delivering effective and persuasive business communications. The ideal candidate can think at the strategic and conceptual level and act, simultaneously, as a highly-effective and productive individual contributor. The position is based in Seattle, WA. For additional information click here
Lilly Singapore Center for Drug Discovery (LSCDD) - Associate Director of Informatics, Lead and mentor a strong team for the Bioinformatics group at the Integrative Computational Sciences (ICS) department at LSCDD towards the development of novel algorithms, data analysis methods and software tools for drug discovery. Work closely with the Software Engineering group at ICS, and collaborate with the Discovery IT organization in Europe and USA. For additional information, or to apply visit: LSCDD
Lilly Singapore Center for Drug Discovery (LSCDD)- Senior Bioinformatics Scientist, Contribute to the development of novel algorithms, data analysis methods and software tools for drug discovery as part of the Integrative Computational Sciences (ICS) department at LSCDD. Work closely with informatics and software engineering peers at ICS, and collaborate with the Discovery IT organization in Europe and USA. The successful candidate will offer hands-on insight and expertise in tailored therapeutic informatics and statistical analyses at the post-genomic era. For additional information, or to apply visit: LSCDD
Lilly Singapore Center for Drug Discovery (LSCDD) - Manager, Software Engineering (Integrative Computational Sciences)
Join the Integrative Computational Sciences (ICS) department at Lilly Singapore Centre for Drug Discovery (LSCDD),as Manager Software Engineering. Lead the development of integrated applications to process and visualize data from cutting edge technologies used by scientists at Lilly Research Labs (LRL) and the Drug Discovery Research (DDR) teams. Masters in Computer Science/Engineering or related discipline, 10+ years post graduation experience , 2 years management experience needed. For a complete job description and requirements or to apply visit: LSCDD
Lilly Singapore Center for Drug Discovery(LSCDD) -Senior Software Engineer,
Join a strong team of software engineers in our Integrative Computational Sciences (ICS) at LSCDD. Collaborate with, and help develop integrated applications to process and visualize data from cutting-edge technologies used by scientists at Lilly Research Labs (LRL) and the Drug Discovery Research (DDR) teams. The Software Engineering team provides computational tools and tailored software solutions that enable the global effort of Tailored Therapeutics; ‘The Right Drug, at The Right Dose for The Right Patient at The Right Time'. For additional information, or to apply visit: LSCDD
Memorial Sloan-Kettering Cancer Center - Linux Systems Administrator MSKCC Bioinformatics Core in Manhattan seeks Linux Systems Administrator. Install, configure, update, monitor and troubleshoot HPC cluster, email and web servers. Bachelor's degree and 3 years experience with HPC, network security, Postfix, Apache, Tomcat, Grid Engine, Solaris. Email [email protected] orwww.mskcc.org #015429. EOE/AA
More Life Science Jobs ~ Add a Job Listing
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FEATURED EVENTS
ELNs: Advanced Laboratory Solutions-September 15 - 17 2008 • Crowne Plaza, Brussels, Belgium
Discovery Knowledge & Informatics - September 15 - 17, 2008 • Crowne Plaza, Brussels, Belgium
Multiplexed Genomics Tools: Targeting the Missing Links
Between Health and Disease - September 21-23, 2008 • Providence, RI
Next-Generation Sequencing Data Analysis -September 22-23, 2008 • Providence, RI
DIA 2nd Annual Clinical Forum: Data Driven Drug Development Decisions - October 20-23, 2008 | Ljubljana, Slovenia
The Fifteenth Annual Biopharmaceutical Applied Statistics Symposium - Nov 3-7,2008~ Savannah, GA
Barnett Educational Services, 2008 Schedule
To have your event featured here, contact Lynn Cloonan for more information.
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| FEATURED CONTENT |
“Storage for Science – Methods for Managing Large and Rapidly Growing Data Stores in Life Science Research Environments” sponsored by Isilon Large and rapidly growing stores of file-based and other data are a hallmark of life science research and bioinformatics. Determining how best to manage those data stores has become a significant challenge for Researchers and IT Pros alike. This paper is intended to: Provide guidance on the many storage requirements common to Life Science research; Explain the evolution of modern storage architectures; Summarize the major data storage architectures currently in use. Additionally, it will present the Isilon IQ clustered storage product as a strong and flexible solution to those needs. Download now
Will Healthcare IT Trends Standardize? A new wave of activities are driving transformation within the healthcare market. One solution is found in a guide to PDF Healthcare Best Practices. This “Best Practices Guide” describes Portable Document Format (PDF) attributes and use to facilitate the capture, exchange, preservation and protection of healthcare information. This webinar will focus on trends in today’s healthcare market, the challenges in overcoming these issues, and finally how to use best practices to improve patient care, enhance productivity and eliminate paperwork. It’s hosted by Adobe and moderated by Digital Healthcare & Productivity Executive Editor, John Russell. Click here...
To have your white paper featured here, contact Lynn Cloonan for more information.
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| EXCLUSIVE WEBCAST |
Life Science Webcasts from Bio-IT World and Cambridge Healthtech Media Group
Bio-IT World Expo
Video Highlights
Drug Discovery, Development and Commercialization: Evolving Challenges and Opportunities Joshua Boger, PhD, president and CEO, Vertex Pharmaceuticals Inc., delivers his keynote at the 2008 Bio-IT World Conference & Expo in Boston, April 30, 2008. View the webcast.
Personalized Genetics: Advancements and Driving Change Linda Avey, co-founder of 23andMe, delivers her keynote at the 2008 Bio-IT World Conference & Expo in Boston, April 30, 2008. View the webcast.
The Future of Personal Genomics A distinguished panel of personal genomics experts discuss the future of personal genomics at the 2008 Bio-IT World Conference & Expo in Boston, April 30, 2008. They include Dietrich Stephan (co-founder, Navigenics); George Church (Harvard Medical School); Jeff Drazen (editor-in-chief, New England Journal Medicine); Fred Ledley (Bentley College); John Halamka (CIO, Harvard Medical School); and Linda Avey (23andMe). Bio-IT World Editor-in-Chief Kevin Davies moderates the discussion. View the webcast.
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| Contact the Editor |
We invite your comments and feedback for this edition of Weekly Update.
Web Editor
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