|
Sales Contacts
For advertising information contact: Alan El Faye
VP, Advertising Sales - CA, Western US, Canada, Pacific Rim
213-300-3886
Kay O. Christopher
Regional Sales Manager, Advertising Sales -New England, North Eastern US
860-693-2991
Tom Loughran
Regional Sales Manager, Advertising Sales -Midwest, South Eastern US, Europe
781-972-5482
|
|
Link to Us!
You are welcome to link to articles on our website. Contact Catherine Varmazis for details.
e-Prints & Reprints
To post a full article from Weekly Update or Bio-IT World on your website (not just a link), or for paper reprints, please contact:
Ashley Zander
The YGS Group
717-399-1900 ext.125
|
|
|
|
| IN THIS ISSUE |
|
A September (2008) to Remember
|
|
BRIDG Moves Toward Double Layer of Semantics |
|
Breathing New Life into Old Drugs
|
|
The Promise of Predictive Modeling in Drug Discovery
|
|
|
| |
| THIS WEEK IN BIO-IT |
| |
A September (2008) to Remember
By Michael Greeley
It has been shown over the many investment cycles that some of the most compelling companies are born in the most turbulent of economic times. As bad as it is now, economic cycles do just that – cycle. Venture capitalists (VCs) by profession accept significant investment risk every day; the good investors will have appropriately long horizons but will insist that value is being created all along the way. Read more.
|
|
| |
BRIDG Moves Toward Double Layer of Semantics
By Deborah Borfitz
Subject matter experts and information technology (IT) professionals involved in clinical trials should both be happier with the next release of BRIDG (Biomedical Research Integrated Domain Group), the domain analysis model aimed at synchronizing semantics within the clinical research and healthcare enterprises. Semantically speaking, BRIDG will be taking a “two-layer approach” that incorporates accepted clinical terminology and definitions as well as technical representations around which software programs and messages can be written. Read more.
|
|
| |
Last Week's Most-Read Bio-IT World Story
Big Pharma's Road to Enlight(enment)
|
|
| |
Bio-IT Briefs - Sept. 24, 2008
- Tibco and Integromics announce genomics data analysis solution
- NIH announces $138M for Director's Pioneer and New Innovator Awards
- Sigma-Aldrich publishes in PubMed's peer-reviewed video journal JoVE
- LabKey Software joins BioIT Alliance
- InhibOx and NFCR launch computational drug screening tool
Invitrogen and Applied Biosystems announce divisional structure . . . more
Bio-IT Briefs - Sept. 29, 2008
- Swiss Institute of Bioinformatics completes annotation of human proteins
- Agilent Technologies introduces bioinformatics software providing systems-level microarray analysis. . . more
|
| |
|
|
| |
| |
| ELSEWHERE IN THE PRESS |
| |
Breathing New Life into Old Drugs
Some companies feel that drug repurposing remains a viable alternative to the oft-financially crippling process of getting a new drug from pipeline to market, and one worthy of more consideration. But so far, only ChanTest Corp., based in Cleveland, is solely focused on reincarnating drugs by matching them with ion channel targets. PharmaWeek.
NIH Director Elias Zerhouni Resigning
Dr. Elias A. Zerhouni, director of the National Institutes of Health, who shook up the agency when he barred scientists from consulting for drugmakers, announced that he would leave at the end of October. New York Times.
FDA to Examine Use of Anemia Drugs in Stroke Patients
Federal health regulators said Friday that they were reviewing an experimental use of blockbuster anemia drugs made by Amgen Inc. and Johnson & Johnson that have been associated with higher death rates in a study involving stroke patients. Los Angeles Times.
Lilly CEO Forecasts Drug Maker's Evolution
Eli Lilly and Co. aims to grow leaner and more diverse as it pushes to keep pace with changes spreading through the drug industry, CEO John Lechleiter said in a Wednesday afternoon speech. Google/AP.
Pfizer Moves into Stem Cell Research
Pfizer’s getting into the stem cell business. The company opened a “regenerative medicine unit” in Cambridge, Mass., last spring, and plans to open another similar shop in Cambridge, U.K., in November, Reuters reports. Wall Street Journal blog (free content).
New Pig Model Could Improve Understanding of Cystic Fibrosis
Howard Hughes Medical Institute researchers have developed a new model of cystic fibrosis in pigs that more accurately mimics features of the disease observed in human infants. HHMI News.
|
|
|
BIO-IT WORLD SEPTEMBER 2008
ISSUE HIGHLIGHTS |
| |
|
The Promise of Predictive Modeling in Drug Discovery
By Mike May
Surveying the use of predictive computer modeling in the pharmaceutical business, Howard Asher, CEO of Global Life Sciences, says, “This field is almost in an embryonic state compared to what it could be.” He adds, “Lots of convergence of knowledge must still occur.”
Given Asher’s background, it is no surprise that his idea of convergence depends on better simulations—building and animating 3-D protein models and watching them interact as a disease progresses, regresses, and reacts to therapies. . . But not everyone sees companies clamoring to put predictive computer modeling to work. Read more.
|
|
| |
NEW PRODUCT
Statistical Graphics
Insightful Clinical Graphics (iCG) version 1.1 is now available to define and repurpose statistical graphics across all functional areas in drug discovery, development, and marketing. iCG 1.1 features new graph types and an improved user interface to simplify the creation and re-use of statistical graphics and elimination of redundant work processes.
Product: iCG v. 1.1
Company: Insightful
Available: Now
For More Information: www.insightful.com
|
|
|
| |
|
|
LIFE SCIENCE JOBS
Lilly Singapore Center for Drug Discovery (LSCDD) - Associate Director of Informatics,
Lead and mentor a strong team for the Bioinformatics group at the Integrative Computational Sciences (ICS) department at LSCDD towards the development of novel algorithms, data analysis methods and software tools for drug discovery. Work closely with the Software Engineering group at ICS, and collaborate with the Discovery IT organization in Europe and USA. For additional information, or to apply visit: LSCDD
Lilly Singapore Center for Drug Discovery (LSCDD)- Senior Bioinformatics Scientist,
Contribute to the development of novel algorithms, data analysis methods and software tools for drug discovery as part of the Integrative Computational Sciences (ICS) department at LSCDD. Work closely with informatics and software engineering peers at ICS, and collaborate with the Discovery IT organization in Europe and USA. The successful candidate will offer hands-on insight and expertise in tailored therapeutic informatics and statistical analyses at the post-genomic era. For additional information, or to apply visit: LSCDD
Lilly Singapore Center for Drug Discovery (LSCDD) - Manager, Software Engineering (Integrative Computational Sciences)
Join the Integrative Computational Sciences (ICS) department at Lilly Singapore Centre for Drug Discovery (LSCDD),as Manager Software Engineering. Lead the development of integrated applications to process and visualize data from cutting edge technologies used by scientists at Lilly Research Labs (LRL) and the Drug Discovery Research (DDR) teams. Masters in Computer Science/Engineering or related discipline, 10+ years post graduation experience , 2 years management experience needed. For a complete job description and requirements or to apply visit: LSCDD
Lilly Singapore Center for Drug Discovery(LSCDD) -Senior Software Engineer,
Join a strong team of software engineers in our Integrative Computational Sciences (ICS) at LSCDD. Collaborate with, and help develop integrated applications to process and visualize data from cutting-edge technologies used by scientists at Lilly Research Labs (LRL) and the Drug Discovery Research (DDR) teams. The Software Engineering team provides computational tools and tailored software solutions that enable the global effort of Tailored Therapeutics; ‘The Right Drug, at The Right Dose for The Right Patient at The Right Time'. For additional information, or to apply visit: LSCDD
Merck ~Sr. Computational Biologist
Apply and develop computational biology/informatics techniques to support Oncology drug discovery; collaborate with scientists to develop in-depth understanding of deregulated signaling pathways, discover novel targets and treatment strategies, and identify associated candidate biomarkers. Ph.D. in Computational Biology/Bioinformatics, solid statistics background and hands-on modeling and informatics techniques related to drug discovery experience required. Click to Apply
More Life Science Jobs ~ Add a Job Listing
|
|
| |
FEATURED EVENTS
Harvard Biomed HPC Leadership Summit 2008, October 5~7, 2008, Boston, MA USA
Drug Stability Reporting (eStability) Working Group Vendor Meeting - October 7, 2008
DIA 2nd Annual Clinical Forum: Data Driven Drug Development Decisions October 20-23, 2008 | Ljubljana, Slovenia
The Fifteenth Annual Biopharmaceutical Applied Statistics Symposium - Nov 3-7,2008 ~Savannah, GA
Super Computing ~ November 15-21, Austin, TX
Fifth Annual Molecular Imaging Week ~November 17-19, 2008, La Jolla, CA,
The Next Tool for Healthcare Innovation~ Nov 20, 2008 2pm EST A Complimentary Frost & Sullivan eBroadcast
Barnett Educational Services
To have your event featured here, contact Lynn Cloonan for more information.
|
|
|
|
| CALL FOR PROPOSALS |
2009 Bio-IT World Conference & Expo
We invite you to submit a speaking proposal for consideration by our Advisory Committee for the 7th Annual Bio-IT World Conference & Expo, April 27-29, 2009 at the World Trade Center in Boston.
Six concurrent tracks will focus on these interest areas:
Track 1 – IT Infrastructure & Operations
Track 2 – Informatics for Genomic Medicine
Track 3 – Predictive and in silico Science
Track 4 – Computational Chemistry
Track 5 – Clinical and Medical Informatics
Track 6 – eHealth Solutions
Details here.
Please respond by October 15.
|
|
| FEATURED CONTENT |
|
Managed Innovation,
Assured Compliance
Developing, executing and managing the transformation, analysis and submission of clinical research data with SAS® Drug Development
sponsored by SAS
Discovery organizations are identifying a lot of promising compounds, but clinical research processes haven't kept pace with timely testing of all those potential therapies. This white paper describes how SAS Drug Development supports true innovation across the clinical trial process.
In this white paper you will learn how to:
~Assemble data to foster better collaboration
~Get up-to-date information during clinical trials
~Make informed decisions earlier in the trial process
Download now
Addressing Life Sciences Constantly Growing Data Challenges Research Environments sponsored by BlueArc
The continued explosion of raw experimental data, the increased use of video, the growingadoption of new data retention practices, and the move to high throughput computational workflows are all placing new demands on the way life sciences organizations store and manage their data.
Download this white paper to learn about:
• Factors driving the data explosion in the life sciences
• New data management issues that must be addressed
• HPC trends that are placing new demands on storage
• Storage solution attributes that address performance, manageability, and energy efficiency. Download now
Hospital Paperwork
No Longer Has to Be an In-patient Procedure
sponsored by Adobe
How many times have you filled out that same patient registration form when visiting a doctor or the hospital? If you are a hospital administrator, nurse or registrar, you know that your patients and particularly your staff have managed hundreds of consent forms for medication, procedures, anesthesia, and HIPAA. Paperwork redundancy has become a significant bottleneck in the healthcare system. In this podcast, we’ll learn about how Adobe solutions for healthcare can help you streamline your paperwork and stop making paperwork an in-patient procedure. Download Now
Microsoft’s BioIT Alliance
Bio-IT World published a special supplement with support from Microsoft and their Alliance members. The supplement provides insight into the activities of the Alliance and their partners. Click here to access the Supplement PDF.
To have your white paper featured here, contact Lynn Cloonan for more information.
|
|
| EXCLUSIVE WEBCAST |
Life Science Webcasts from Bio-IT World and Cambridge Healthtech Media Group
Bio-IT World Expo
Video Highlights
Drug Discovery, Development and Commercialization: Evolving Challenges and Opportunities
Joshua Boger, PhD, president and CEO, Vertex Pharmaceuticals Inc., delivers his keynote at the 2008 Bio-IT World Conference & Expo in Boston, April 30, 2008.
View the webcast.
Personalized Genetics: Advancements and Driving Change
Linda Avey, co-founder of 23andMe, delivers her keynote at the 2008 Bio-IT World Conference & Expo in Boston, April 30, 2008.
View the webcast.
The Future of Personal Genomics
A distinguished panel of personal genomics experts discuss the future of personal genomics at the 2008 Bio-IT World Conference & Expo in Boston, April 30, 2008. They include Dietrich Stephan (co-founder, Navigenics); George Church (Harvard Medical School); Jeff Drazen (editor-in-chief, New England Journal Medicine); Fred Ledley (Bentley College); John Halamka (CIO, Harvard Medical School); and Linda Avey (23andMe). Bio-IT World Editor-in-Chief Kevin Davies moderates the discussion.
View the webcast.
|
|
| Contact the Editor |
We invite your comments and feedback for this edition of Weekly Update.
Web Editor
|
|