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Sales Contacts
For advertising information contact: Alan El Faye
VP, Advertising Sales - CA, Western US, Canada, Pacific Rim
213-300-3886
Kay O. Christopher
Regional Sales Manager, Advertising Sales -New England, North Eastern US
860-693-2991
Tom Loughran
Regional Sales Manager, Advertising Sales -Midwest, South Eastern US, Europe
781-972-5482
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| IN THIS ISSUE |
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Complete Genomics Service Targets $1000 Genome by Spring 2009 |
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DNA Nanoballs, Petabytes of Data Mark Complete Genomics Platform |
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Lilly Nears Deal to Buy ImClone |
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Putting Semantic Web Ideas to Work |
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Nov./Dec. Bio-IT World Issue Preview
Cover Feature: Personal Genomics’ First Anniversary: A review of the four major consumer genomics services and a look at the pros, cons and controversies surrounding this emerging field.
Pathways for Cancer: Two papers in Science from a leading cancer group at Johns Hopkins are remarkable not only for their insights into the mutational complexity of cancer, but for the application of predictive pathway software.
Complete Genomics: The launch of a new Bay Area company in early October promises to shake up the next-generation sequencing field, as they promise a $5000 genome in 2009.
Pharma Workflow: How Tripos and Accenture collaborated to make discovery scientists more productive at Wyeth.
European Economic Development: A special report on life science/biotech development trends, with reports from Denmark, The Netherlands, and Spain.
To advertise, contact Alan El Faye at 213-300-3886, Kay O. Christopher at 860-693-2991, or Tom Loughran at 781-972-5482.
Ad Closing: Oct. 14, 2008
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| THIS WEEK IN BIO-IT |
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Complete Genomics Service Targets $1000 Genome by Spring 2009
By Kevin Davies
Complete Genomics emerged from stealth mode today brandishing an audacious service model for wholesale next-generation sequencing, with its first human genome already assembled and the CEO’s pledge to reach the magical “$1000 genome” price point as early as spring 2009.
“Our mission is to be the global leader in complete human genome sequencing,” chairman, president and CEO Clifford Reid told Bio-IT World in a briefing last week. “We are setting out to completely change the economics of genome sequencing so that we can do diagnostic quality human genome sequencing at a medically affordable price. Essentially, [we’ll] transition this genome sequencing world from a scientific and academic endeavor into a pharmaceutical and medical endeavor.” Read more.
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DNA Nanoballs, Petabytes of Data Mark Complete Genomics Platform
By Kevin Davies
With the unveiling today of the next phase of the next-generation sequencing era by Complete Genomics (see accompanying Bio-IT World story) comes intense scrutiny of the sequencing-by-
hybridization (SBH) strategy that the company says will deliver one million genome sequences in the next five years. The technology hinges on exquisite precision in manufacturing and arraying “nanoballs” of DNA as well as the ability to manage gargantuan quantities of data.
Last week, Bio-IT World spoke to the two men directing the sequencing and data handling aspects of Complete Genomics’ new sequencing service. Read more.
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Pathway Tools Shine, GeneGo Basks in the Spotlight
By John Russell
The attention being given to two recent Science papers suggesting pathways, not genes, are better targets for solid cancer tumor treatment is good news for all pathway tool providers. Such tools were important in this work by prominent cancer researchers. The attention is especially sweet for GeneGo which provided tools and data analysis, and had two authors, Tatiana Nikolskaya (president and CSO) Yuri Nikolsky (CEO), on the papers. Read more.
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Last Week's Most-Read Bio-IT World Story
The Promise of Predictive Modeling in Drug Discovery
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Bio-IT Briefs - Oct. 2, 2008
- Applied Biosystems debuts new SOLiD 3 System expected to enable $10K genome
- Progeniq’s BoostServe Extreme provides 1000x acceleration for selected bioinformatics applications
- Swedish Neuroscience Institute and Institute for Systems Biology form alliance to learn more about brain diseases
- RainDance, Sanofi-Aventis and Louis Pasteur U. to launch dScreen Consortium within Alsace Biovalley cluster
- Congress votes to create national registry for ALS . . . more
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| ELSEWHERE IN THE PRESS |
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Lilly Agrees to Buy ImClone Systems for $6.5 Billion
Eli Lilly & Co. agreed to buy ImClone Systems Inc., the biotechnology company controlled by billionaire Carl Icahn, for $6.5 billion, and Bristol-Myers Squibb Co. said it would drop its hostile bid. Bloomberg.
Biochemist Robert Tjian Elected as New HHMI President
The Trustees of the Howard Hughes Medical Institute announced the election of Robert Tjian of the University of California, Berkeley, as the Institute's new president. HHMI News.
23andMe Launches Breast Cancer Networking Project
Personal genomics company 23andMe announced the debut of a new initiative to bring together women who have been affected by breast cancer or who may be genetically at risk. CNet News.
Prolong Pharmaceuticals – PEGged For Success?
New Jersey-based Prolong Pharmaceuticals is attaching polyethylene glycol (PEG) to a variety of protein-based drugs. Or, to use the proper term, “pegylating” these drugs to improve pharmacokinetics, extend circulation time and decrease toxicity, all of which make for enhanced therapeutic effects. PharmaWeek.
FDA Awards $2.5 Billion to Modernize IT Infrastructure
The FDA announced the selection of 10 contractors to receive up to a total of $2.5 billion for information technology and data center management services over the next 10 years. FDA News.
Cambridge Biotech Raises $40m to Test Alzheimer's Drug
Boston Globe | Link Medicine Corp., a Cambridge biotech company, plans to say today that it raised $40 million in additional venture funding to help launch clinical trials for its lead drug, a pill designed to treat Alzheimer's and Parkinson's diseases.. Boston Globe.
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BIO-IT WORLD SEPTEMBER 2008
ISSUE HIGHLIGHTS |
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Putting Semantic Web Ideas to Work
By John Russell
Turning Semantic Web technology into practical applications that enhance biomedical research was a driving force behind Robert Stanley’s and Erich Gombocz’s collaboration long before they founded IO Informatics. The explosion of data and the scientific literature convinced them that effective data management and data integration were critical for productive data analysis. Read more.
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Going Green for 1000 Genomes
By Kevin Davies
As the NIH 1000 Genomes project kicks into top gear, data center managers are racing to come to terms with the glut of data that they will have to manage from the next-generation sequencing instruments. “This is a problem for all the [genome] centers to deal with, as well as the repositories such as NCBI,” says David Parker, Baylor College of Medicine Human Genome Sequencing Center systems analyst. Read more.
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FEATURED EVENTS
DIA 2nd Annual Clinical Forum: Data Driven Drug Development Decisions October 20-23, 2008 | Ljubljana, Slovenia
Super Computing ~ November 15-21, Austin, TX
Fifth Annual Molecular Imaging Week ~November 17-19, 2008, La Jolla, CA,
The Next Tool for Healthcare Innovation~ Nov 20, 2008 2pm EST A Complimentary Frost & Sullivan eBroadcast
The Association for Laboratory Automation (ALA) presents LabAutomation2009, January 24-28, in Palm Springs, CA.
TEPR+ 2009 - Feb 1-5, 2009 | Palm Springs, CA
Barnett Educational Services
Cambridge Healthtech Events
To have your event featured here, contact Lynn Cloonan for more information.
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| CALL FOR PROPOSALS |
2009 Bio-IT World Conference & Expo
We invite you to submit a speaking proposal for consideration by our Advisory Committee for the 7th Annual Bio-IT World Conference & Expo, April 27-29, 2009 at the World Trade Center in Boston.
Six concurrent tracks will focus on these interest areas:
Track 1 – IT Infrastructure & Operations
Track 2 – Informatics for Genomic Medicine
Track 3 – Predictive and in silico Science
Track 4 – Computational Chemistry
Track 5 – Clinical and Medical Informatics
Track 6 – eHealth Solutions
Details here.
Please respond by October 15.
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| FEATURED CONTENT |
Managed Innovation,
Assured Compliance
Developing, executing and managing the transformation, analysis and submission of clinical research data with SAS® Drug Development
sponsored by SAS
Discovery organizations are identifying a lot of promising compounds, but clinical research processes haven't kept pace with timely testing of all those potential therapies. This white paper describes how SAS Drug Development supports true innovation across the clinical trial process.
In this white paper you will learn how to:
~Assemble data to foster better collaboration
~Get up-to-date information during clinical trials
~Make informed decisions earlier in the trial process
Download now
Addressing Life Sciences Constantly Growing Data Challenges Research Environments sponsored by BlueArc
The continued explosion of raw experimental data, the increased use of video, the growingadoption of new data retention practices, and the move to high throughput computational workflows are all placing new demands on the way life sciences organizations store and manage their data.
Download this white paper to learn about:
• Factors driving the data explosion in the life sciences
• New data management issues that must be addressed
• HPC trends that are placing new demands on storage
• Storage solution attributes that address performance, manageability, and energy efficiency. Download now
“Storage for Science – Methods for Managing Large and Rapidly Growing Data Stores in Life Science Research Environments” sponsored by Isilon
Large and rapidly growing stores of file-based and other data are a hallmark of life science research and bioinformatics. Determining how best to manage those data stores has become a significant challenge for Researchers and IT Pros alike. This paper is intended to: Provide guidance on the many storage requirements common to Life Science research; Explain the evolution of modern storage architectures; Summarize the major data storage architectures currently in use. Additionally, it will present the Isilon IQ clustered storage product as a strong and flexible solution to those needs. Download now
Microsoft’s BioIT Alliance
Bio-IT World published a special supplement with support from Microsoft and their Alliance members. The supplement provides insight into the activities of the Alliance and their partners. Click here to access the Supplement PDF.
To have your white paper featured here, contact Lynn Cloonan for more information.
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| EXCLUSIVE WEBCAST |
Life Science Webcasts from Bio-IT World and Cambridge Healthtech Media Group
Bio-IT World Expo
Video Highlights
Drug Discovery, Development and Commercialization: Evolving Challenges and Opportunities
Joshua Boger, PhD, president and CEO, Vertex Pharmaceuticals Inc., delivers his keynote at the 2008 Bio-IT World Conference & Expo in Boston, April 30, 2008.
View the webcast.
Personalized Genetics: Advancements and Driving Change
Linda Avey, co-founder of 23andMe, delivers her keynote at the 2008 Bio-IT World Conference & Expo in Boston, April 30, 2008.
View the webcast.
The Future of Personal Genomics
A distinguished panel of personal genomics experts discuss the future of personal genomics at the 2008 Bio-IT World Conference & Expo in Boston, April 30, 2008. They include Dietrich Stephan (co-founder, Navigenics); George Church (Harvard Medical School); Jeff Drazen (editor-in-chief, New England Journal Medicine); Fred Ledley (Bentley College); John Halamka (CIO, Harvard Medical School); and Linda Avey (23andMe). Bio-IT World Editor-in-Chief Kevin Davies moderates the discussion.
View the webcast.
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| Contact the Editor |
We invite your comments and feedback for this edition of Weekly Update.
Web Editor
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